Dank voor de reacties. Inderdaad eerst maar een softwarematig nalopen.
1. Een nieuw account aanmaken had ik al geprobeerd, die liep ook vast.
2. Gisteravond EtreCheck en laten draaien, zie hieronder het rapport. Ben er vanochtend zelf ook doorheen gaan kijken.
3. Inmiddels alweer twee dagen geleden, een beachball.
Zoals je in het rapport kunt zien ben ik nog niet zo lang geleden naar Catalina overgestapt. Ik vraag me ook af of de combi McAfee en Catalina de boosdoener zou kunnen zijn. Hier moet ik echter gebruik van maken, i.c.m. met GlobalProtect om op het bedrijfsnetwerk op te kunnen. Heb op internet wel wat posts gevonden over memory-leaks bij McAfee en Catalina. 
Ik zie ook enkele apps (Skitch, SoapUI, VirtualBox en Docker) waar ik wel vanaf zou kunnen. Die staan er echter al zolang op; die hebben eerder geen problemen gegeven.
Trouwens, wat is het verschil tussen Launch Agents en Daemons?
===================================================
EtreCheck version: 5.6 (5212)
Report generated: 2020-09-22 22:45:56
Download EtreCheck from 
https://etrecheck.comRuntime: 2:17
Performance: Excellent
Sandbox: Enabled
Full drive access: Disabled
Problem: Beachballing
Major Issues:
  Anything that appears on this list needs immediate attention. 
  Unsigned files - There are unsigned software files installed that could be adware and should be reviewed.
Minor Issues:
  These issues do not need immediate attention but they may indicate future problems or opportunities for improvement. 
  Unsigned files - There are unsigned software files installed. Apple has said that unsigned software will not run by default in a future version of the operating system.
  32-bit Apps - This machine has 32-bits apps will not work on current versions of the operating system.
  Limited drive access - More information may be available with Full Drive Access.
  Kernel extensions present - This machine has kernel extensions that may not work in the future.
Hardware Information:
  MacBook Pro (15-inch, 2017)
  MacBook Pro Model: MacBookPro14,3
  2.80 GHz Quad-Core Intel Core i7 (i7-7700HQ) CPU: 4-core
  16 RAM - Not upgradeable
    BANK 0/DIMM0 - 8 GB LPDDR3 2133  
    BANK 1/DIMM0 - 8 GB LPDDR3 2133  
  Battery: Health = Normal - Cycle count = 164
Video Information:
  Intel HD Graphics 630 - VRAM: 1536 MB
    Color LCD (built-in) 3360 x 2100
  Radeon Pro 555 - VRAM: 2 GB
Drives:
  disk0 - APPLE SSD SM0512L 500.28 GB (Solid State - TRIM: Yes) 
  Internal PCI-Express 8.0 GT/s x4 NVM Express
    disk0s1 - EFI [EFI] 315 MB
    disk0s2 [APFS Container] 499.96 GB
      disk1 [APFS Virtual drive] 499.96 GB (Shared by 5 volumes)
        disk1s1 - Macintosh HD - Data (APFS) [APFS Virtual drive] (Shared - 286.51 GB used)
        disk1s2 - Preboot (APFS) [APFS Preboot] (Shared)
        disk1s3 - Recovery (APFS) [Recovery] (Shared)
        disk1s4 - VM (APFS) [APFS VM] (Shared - 1.07 GB used)
        disk1s5 - Macintosh HD (APFS) (Shared - 11.09 GB used)
Mounted Volumes:
  disk1s1 - Macintosh HD - Data [APFS Virtual drive]
    499.96 GB (Shared - 286.51 GB used, 232.20 GB available, 199.45 GB free)
    APFS
    Mount point: /System/Volumes/Data
    Encrypted
  disk1s4 - VM [APFS VM]
    499.96 GB (Shared - 1.07 GB used, 199.45 GB free)
    APFS
    Mount point: /private/var/vm
  disk1s5 - Macintosh HD
    499.96 GB (Shared - 11.09 GB used, 232.20 GB available, 199.45 GB free)
    APFS
    Mount point: /
    Encrypted
    Read-only: Yes
Network:
  Interface en7: Dell Universal Dock D6000
  Interface en8: USB 10/100/1000 LAN
  Interface en9: Dell Universal Dock D6000 2
  Interface en0: Wi-Fi
    802.11 a/b/g/n/ac
  Interface en6: Bluetooth PAN
  Interface bridge0: Thunderbolt Bridge
System Software:
  macOS Catalina 10.15.6 (19G2021) 
  Time since boot: Less than an hour
Configuration Files:
  /etc/hosts - Count: 1
Notifications:
  Notifications not available without Full Drive Access.
Security:
  Gatekeeper: Enabled
  System Integrity Protection: Enabled
  Antivirus software: Apple and McAfee
Unsigned Files:
  Launchd: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/com.oracle.java.Helper-Tool.plist
    Executable: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/Helper-Tool
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/com.mcafee.aac.plist
    Executable: 
  Launchd: /Library/LaunchDaemons/com.mcafee.agent.macompat.plist
    Executable: 
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/com.mcafee.ssm.Eupdate.plist
    Executable: /usr/local/McAfee/AntiMalware/VShieldUpdate
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/com.oracle.java.Helper-Tool.plist
    Executable: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/Helper-Tool
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/org.virtualbox.startup.plist
    Executable: /Library/Application Support/VirtualBox/LaunchDaemons/VirtualBoxStartup.sh restart
    Details: Exact match found in the legitimate list - probably OK
  Launchd: ~/Library/LaunchAgents/com.google.keystone.agent.plist
    Executable: ~/Library/Google/GoogleSoftwareUpdate/GoogleSoftwareUpdate.bundle/Contents/Resources/GoogleSoftwareUpdateAgent.app/Contents/MacOS/GoogleSoftwareUpdateAgent -runMode ifneeded
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/com.oracle.java.Java-Updater.plist
    Executable: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/Java Updater.app/Contents/MacOS/Java Updater -bgcheck
    Details: Exact match found in the legitimate list - probably OK
  Launchd: ~/Library/LaunchAgents/com.google.keystone.xpcservice.plist
    Executable: ~/Library/Google/GoogleSoftwareUpdate/GoogleSoftwareUpdate.bundle/Contents/Resources/GoogleSoftwareUpdateAgent.app/Contents/MacOS/GoogleSoftwareUpdateAgent -runMode xpchost
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchAgents/com.oracle.java.Java-Updater.plist
    Executable: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Resources/Java Updater.app/Contents/MacOS/Java Updater -bgcheck
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/com.mcafee.virusscan.fmpd.plist
    Executable: /usr/local/McAfee/fmp/bin64/fmpd
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/com.mcafee.ssm.ScanManager.plist
    Executable: /usr/local/McAfee/AntiMalware/VShieldScanManager
    Details: Exact match found in the legitimate list - probably OK
  Launchd: /Library/LaunchDaemons/com.mcafee.ssm.ScanFactory.plist
    Executable: /usr/local/McAfee/AntiMalware/VShieldScanner
    Details: Exact match found in the legitimate list - probably OK
  Plugin: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin
  Preference Pane: /Library/Internet Plug-Ins/JavaAppletPlugin.plugin/Contents/Home/lib/deploy/JavaControlPanel.prefPane
  Apps: 2
32-bit Applications:
  7 32-bit apps
Kernel Extensions:
  /Applications/GlobalProtect.app
    gplock.kext (5.0.0 - SDK 10.10)
    gpsplit.kext (5.0.0 - SDK 10.10)
    pangpd_10.9.kext (1.0.0 - SDK 10.9)
  /Library/Application Support/Citrix Receiver
    CitrixGUSB.kext (20.8.0 - SDK 10.9)
  /Library/Application Support/VirtualBox
    VBoxDrv.kext (6.0.12)
    VBoxNetAdp.kext (6.0.12)
    VBoxNetFlt.kext (6.0.12)
    VBoxUSB.kext (6.0.12)
System Launch Agents:
  [Not Loaded]  16 Apple tasks
  [Loaded]  182 Apple tasks
  [Running]  115 Apple tasks
System Launch Daemons:
  [Not Loaded]  34 Apple tasks
  [Loaded]  174 Apple tasks
  [Running]  129 Apple tasks
Launch Agents:
  [Loaded] com.citrix.AuthManager_Mac.plist (Citrix Systems, Inc. - installed 2020-08-26)
  [Running] com.citrix.ReceiverHelper.plist (Citrix Systems, Inc. - installed 2020-08-26)
  [Running] com.citrix.ServiceRecords.plist (Citrix Systems, Inc. - installed 2020-08-26)
  [Not Loaded] com.displaylink.loginscreen.plist (DisplayLink Corp - installed 2020-08-07)
  [Running] com.mcafee.menulet.plist (McAfee, Inc. - installed 2019-10-11)
  [Running] com.mcafee.reporter.plist (McAfee, Inc. - installed 2019-10-11)
  [Not Loaded] com.oracle.java.Java-Updater.plist (? e560d694  - installed 2019-08-19)
  [Running] com.paloaltonetworks.gp.pangpa.plist (Palo Alto Networks - installed 2019-08-19)
  [Running] com.paloaltonetworks.gp.pangps.plist (Palo Alto Networks - installed 2019-08-19)
Launch Daemons:
  [Loaded] com.apple.installer.osmessagetracing.plist (Apple - installed 2020-06-03)
  [Loaded] com.citrix.ctxusbd.plist (Citrix Systems, Inc. - installed 2020-08-26)
  [Running] com.docker.vmnetd.plist (Docker Inc - installed 2020-01-31)
  [Not Loaded] com.mcafee.aac.plist (? 0  - installed 2019-10-25)
  [Running] com.mcafee.agent.ma.plist (McAfee, Inc. - installed 2019-11-09)
  [Running] com.mcafee.agent.macmn.plist (McAfee, Inc. - installed 2019-11-09)
  [Not Loaded] com.mcafee.agent.macompat.plist (? 0  - installed 2019-11-09)
  [Running] com.mcafee.ssm.Eupdate.plist (? 0  - installed 2019-11-02)
  [Running] com.mcafee.ssm.ScanFactory.plist (? 0  - installed 2019-11-02)
  [Running] com.mcafee.ssm.ScanManager.plist (? 0  - installed 2019-11-02)
  [Running] com.mcafee.virusscan.fmpd.plist (? 0  - installed 2019-10-25)
  [Not Loaded] com.oracle.java.Helper-Tool.plist (? e3fefdd2  - installed 2019-08-19)
  [Not Loaded] com.paloaltonetworks.gp.pangpsd.plist (Palo Alto Networks - installed 2019-08-19)
  [Not Loaded] org.virtualbox.startup.plist (? 700b9385  - installed 2019-09-20)
User Launch Agents:
  [Loaded] com.google.keystone.agent.plist (? 0  - installed 2020-08-24)
  [Loaded] com.google.keystone.xpcservice.plist (? 0  - installed 2020-08-24)
User Login Items:
  [Not Loaded] DisplayLinkLoginHelper (DisplayLink Corp - installed 2020-09-08)
    Modern Login Item
    /Applications/DisplayLink Manager.app/Contents/Library/LoginItems/DisplayLinkLoginHelper.app
  [Loaded] DockerHelper (Docker Inc - installed 2020-01-31)
    Modern Login Item
    /Applications/Docker.app/Contents/Library/LoginItems/DockerHelper.app
  [Not Loaded] Skitch Helper (App Store - installed 2020-07-14)
    Modern Login Item
    /Applications/Skitch.app/Contents/Library/LoginItems/J8RPQ294UB.com.skitch.SkitchHelper.app
  [Not Loaded] HDXCastHelper (Citrix Systems, Inc. - installed 2020-09-03)
    Modern Login Item
    /Library/Application Support/Citrix Receiver/Citrix Casting.app/Contents/Library/LoginItems/HDXCastHelper.app
Internet Plug-ins:
  JavaAppletPlugin: Java 8 Update 221 build 11 (? - installed 2019-08-19)
User Internet Plug-ins:
  User Internet Plug-ins need Full Drive Access
User Audio Plug-ins:
  User Audio Plug-ins need Full Drive Access
User iTunes Plug-ins:
  User iTunes Plug-ins need Full Drive Access
3rd Party Preference Panes:
  Java (? - installed 2019-07-04)
Backup:
  Time Machine information not available without Full Drive Access.
  9 local snapshots
  Oldest local snapshot: 2020-09-18 10:51:38
  Last local snapshot: 2020-09-22 18:29:22
Performance:
  System Load: 6.62 (1 min ago) 4.58 (5 min ago) 1.99 (15 min ago)
  Nominal I/O speed: 16.56 MB/s
  File system: 29.10 seconds
  Write speed: 1807 MB/s
  Read speed: 285 MB/s
CPU Usage Snapshot:
  Type Overall
  System: 4 %
  User: 10 %
  Idle: 86 %
Top Processes Snapshot by CPU:
  Process (count) CPU (Source - Location)
  Other processes 64.72 % (?)
  EtreCheck 22.24 % (App Store)
  trustd 12.70 % (Apple)
  Activity Monitor 5.13 % (Apple)
  cloudd 1.23 % (Apple)
Top Processes Snapshot by Memory:
  Process (count) RAM usage (Source - Location)
  EtreCheck 538 MB (App Store)
  Activity Monitor 117 MB (Apple)
  Dock 116 MB (Apple)
  App Store 93 MB (Apple)
  accountsd 78 MB (Apple)
Top Processes Snapshot by Network Use:
  Process (count) Input / Output (Source - Location)
  Other processes 196 KB / 157 KB (?)
  SystemUIServer 0 B / 64 B (Apple)
  spindump_agent 0 B / 0 B (Apple)
  backgroundtaskmanagementagent 0 B / 0 B (Apple)
  SafariBookmarksSyncAgent 0 B / 0 B (Apple)
Virtual Memory Information:
  Physical RAM: 16 GB
  Free RAM: 8.09 GB
  Used RAM: 4.38 GB
  Cached files: 3.53 GB
  Available RAM: 11.62 GB
  Swap Used: 0 B
Software Installs (past 30 days):
  Install Date Name (Version)
  2020-08-28 macOS Catalina (10.15.6)
  2020-08-28 MRTConfigData (1.66)
  2020-09-03 Citrix Workspace (20.8.0)
  2020-09-08 DisplayLink Manager (1.1.0 (91))
  2020-09-08 DisplayLink login screen extension (1.0.1.74)
  2020-09-17 Safari (14.0)
  2020-09-18 XProtectPlistConfigData (2131)
  2020-09-18 Xcode (12.0)
  2020-09-22 Keynote (10.0)
  2020-09-22 Pages (10.0)
  2020-09-22 Numbers (10.0)
  2020-09-22 EtreCheck (5.6)
Diagnostics Information (past 7-30 days):
  Directory /Library/Logs/DiagnosticReports is not accessible.
  Enable Full Drive Access to see more information.
End of report
===================================================